대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	Environment-wide Association Study of Metabolic Syndrome
저자	Jeonghwan Lee, Sohee Oh, Jung Nam An, Yun Kyu Oh, Chun Soo Lim, Dong Ki Kim, Yon Su Kim, Kyungho Choi, Jung Pyo Lee,
출판정보	2020; 2020(1):
키워드	environmental chemicals \| metabolic syndrome \| volatile organic compound \| polyaromatic hydrocarbons \| polychlorinated biphenyl
초록	Environmental chemicals might be possible factors for metabolic syndrome. We aimed to identify environmental chemicals that are associated with the prevalence of metabolic syndrome. We analyzed the data obtained from a total of 46,748 adults who participated in the National Health and Nutrition Examination Survey (NHANES, 1999-2016). Metabolic syndrome was defined following the NCEP ATP III 2005 criteria. Associations of chemicals measured in urine or blood (n = 262) with metabolic syndrome were tested and validated using the environment-wide association study (EWAS) approach. Among 262 environmental chemicals, 66 (25.2%) chemicals showed significant associations with metabolic syndrome. Among them, 13 chemicals (5.0%) of chemicals were associated with increased risk of metabolic syndrome. Discovered and validated environmental chemical are as follows: seven chemicals in serum dioxin or polychlorinated biphenyl group (PCB74, PCB118, 1,2,3,4,6,7,8,9-ocdd, 1,2,3,4,7,8-hcxdf, heptachlor epoxide, oxychlordane, 3,3',4,4',5-pncb), 4 blood pesticides (Beta-hexachlorocyclohexane, Dieldrin, p,p'-DDT, Trans-nonachlor), 1 polycyclic aromatic hydrocarbons (2-phenanthrene), and 1 blood volatile organic compound (nitromethane). A number of chemicals were identified as potential risk factors for metabolic syndrome among the general US population.
원문(PDF)	PDF 원문보기

목록

위로가기