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논문분류	춘계학술대회 초록집
제목	Plasma Levels of Vitamin D Based on Blood Pressure in Obese Adolescent Boys
저자	Alim Musarofah, Dian Caturini S, B.Sc., M.Sc
출판정보	2020; 2020(1):
키워드	Vitamin D \| Blood Pressure \| Hypertension \| Obesity \| Adolescence
초록	Between 2007 and 2013, the prevalence of adolescent obesity in Indonesia increased 5.9%, from 1.4% to 7.3%. Obesity in adolescence is a major concern, not only because it may develop into adulthood obesity, but it also contributes to risk of cardiovascular disease, particularly high blood pressure. The risk is higher in boys than girls. Latest trend of previous studies has presented that low vitamin D levels are associated with high blood pressure or hypertension. On the other hand, several studies have reported that low vitamin D levels are common in individuals with obesity. The objective of this study is to examine plasma levels of vitamin D based on blood pressure in obese adolescent boys. This study is an observational analytic study with cross-sectional design. Subjects were 57 adolescent boys aged 15–18 years with obesity. Obesity was determined by anthropometric BMI-for-age z-scores. Blood pressure was measured by sphygmomanometer in seated rest condition. Vitamin D levels were determined by plasma 25(OH)D levels using ELISA EIA 5396. Data were analyzed by Mann-Whitney U test to determine the differences of vitamin D levels based on blood pressure classification, and Spearman’s correlation test to assess the association among those variables. Based on the blood pressure, subjects were 63.2% relatively high and 36.8% classified as normal. All subjects (n=57) were classified as vitamin D deficiency (plasma levels of 25(OH)D <20ng/ml). There were no differences of vitamin D levels between high and normal blood pressure groups (p=0.118). No significant association was found between vitamin D levels with systolic (r=–0.150, p=0.267) and diastolic blood pressure (r=–0.157, p=0.244). There were no differences in plasma levels of vitamin D based on normal and high blood pressure groups. Although it showed a negative relationship, there was no significant association between vitamin D levels and both systolic and diastolic blood pressure.
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