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논문분류	춘계학술대회 초록집
제목	Diagnostic Accuracy of Rapid Antibody Testing in Hemodialysis Patients
저자	Rommel Bataclan
출판정보	2021; 2021(1):
키워드
초록	Objective: Blood samples were taken in RT-PCR negative hemodialysis patients without any history of COVID-19 diagnosis and two groups of COVID-19 hemodialysis patients: those who were recently diagnosed (within 1-2 weeks) and those with previous history of COVID-19 infection who recovered. The samples were tested using LUNGENE IgG/IgM Rapid Test Cassette. Those who are recently diagnosed with COVID-19 were tested at the time of recruitment and a month after the diagnosis. Methods: Among those recently diagnosed hemodialysis patients, the IgM test showed 87.5% sensitivity, 98.7% specificity, 92.8% PPV and 97.7% NPV. The IgG test among these patients at about 1-2 weeks time showed 85.3% Sensitivity, 96.1% Specificity, 80% PPV and 96.4% NPV. Including those diagnosed with COVID at least more than a month prior, the IgG test showed 92.1% Sensitvity, 93.7% Specificity, 88.3% PPV and 95% NPV. Results: The LUNGENE IgG/IgM Rapid Test displayed a high diagnostic accuracy among hemodialysis patients, where its use could be considered in the absence of routine diagnostic serology facilities. Conclusions: Objective: Antibody testing though not a diagnostic tool and surrogate of individual protection, it may be used for seroprevalence and evaluate effectiveness of screening and preventive measures. This study investigates the diagnostic accuracy of a rapid antibody test among hemodialysis patients. Methods: Blood samples were taken in RT-PCR negative hemodialysis patients without any history of COVID-19 diagnosis and two groups of COVID-19 hemodialysis patients: those who were recently diagnosed (within 1-2 weeks) and those with previous history of COVID-19 infection who recovered. The samples were tested using LUNGENE IgG/IgM Rapid Test Cassette. Those who are recently diagnosed with COVID-19 were tested at the time of recruitment and a month after the diagnosis. Results: Among those recently diagnosed hemodialysis patients, the IgM test showed 87.5% sensitivity, 98.7% specificity, 92.8% PPV and 97.7% NPV. The IgG test among these patients at about 1-2 weeks time showed 85.3% Sensitivity, 96.1% Specificity, 80% PPV and 96.4% NPV. Including those diagnosed with COVID at least more than a month prior, the IgG test showed 92.1% Sensitvity, 93.7% Specificity, 88.3% PPV and 95% NPV. Conclusions: The LUNGENE IgG/IgM Rapid Test displayed a high diagnostic accuracy among hemodialysis patients, where its use could be considered in the absence of routine diagnostic serology facilities.
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