대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	Albuminuria and Young Age Onset Diabetes: A Nationwide Population-based Study
저자	Yaerim Kim
출판정보	2023; 2023(1):
키워드
초록	Backgrounds: Early-onset diabetes is associated with increased morbidity and mortality and a substantial lifetime burden. Since insulin resistance is one of the mechanisms of podocyte injury, we tried to determine the predictability of albuminuria for newly diagnosed type 2 diabetes with early onset. Methods: We screened 6,891,399 subjects aged ≥20 and <40 years without a history of impaired glucose tolerance or diabetes from the Korean National Health Insurance Service database between 2009 and 2012. A multivariate Cox proportional hazard model was used to identify the impact of albuminuria on early-onset diabetes. Results: Among a total of 5,383,779 subjects, 62,148 (1.2%) subjects developed early-onset diabetes over 7.3±1.2 years. Albuminuria significantly increased the risk of early-onset type 2 diabetes (adjusted hazard ratio (aHR) 1.62, 95% confidence interval (CI) 1.55, 1.70) after adjustment for age, sex, anthropometric data, physical exercise status, serum glucose, and total cholesterol. The risk of early-onset type 2 diabetes increased more in subjects with more components of metaobolic syndrome (MetS). In subjects with albuminuria, hypertriglyceridemia increased the risk of early-onset type 2 diabetes (aHR 2.02, 95% CI 1.81, 2.25). Conclusions: Early-onset diabetes was strongly associated with albuminuria detected by dipstick. In order to reduce the likelihood of developing an illness, people with MetS should have their albuminuria closely monitored.
원문(PDF)	PDF 원문보기

목록

위로가기