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논문분류	춘계학술대회 초록집
제목	The interaction effect of phase angle and age on femoral neck bone mineral density in patients with non-dialysis chronic kidney disease stage 5
저자	Byoung Geun Han
출판정보	2023; 2023(1):
키워드
초록	Objectives: Low bone mass is common in malnourished patients with chronic kidney disease (CKD) and can lead to higher risk of fractures. Elderly and CKD patients have the same risk factors for protein energy wasting, sarcopenia, and osteoporosis. We attempted to investigate an association between phase angle (PhA) and bone mineral density (BMD) in dialysis nave patients with stage 5 CKD, and to identify a statistical relationship between PhA and age that affects bone density. Methods: Bio-impedance spectroscopy for evaluating body composition and PhA and dual energy X-ray absorptiometry for determining the BMD were simultaneously performed in 167 consecutive patients (age: 59.65 ± 13.98 years; women: 40.1%). A two-way analysis of variance was conducted to assess the potential interaction effect of PhA and age on femoral neck BMD. Results: Our results showed that PhA was independently associated with femoral neck BMD and the T-score in multiple linear regressions analyses. Furthermore, the two-way analysis of variance with interaction showed that a statistically significant interaction effect between PhA and age, which implies the effect of PhA levels on femoral neck BMD was different for elderly patients than it was for younger patients. Conclusions: A relationship between PhA and BMD in patients with advanced-stage CKD was identified in current study. An effect of PhA levels on femoral neck BMD was different for elderly patients than it was for younger patients. High PhA may have protective effects on bone health in those patients and seems to be an important determinant for BMD.
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