| 초록 |
Objectives: There is still a lack of evidence that unplanned hemodialysis (HD) treatment significantly increases the mortality in elderly patients with end-stage renal disease (ESRD) compared to planned HD treatment, and prognostic factors are not clear.
Methods: We retrospectively analyzed the medical records of 2,373 patients aged ≥70 years starting HD at 17 university hospitals in the Korean Society of Geriatric Nephrology (KSGN) between 1 January 2010 and 31 December 2017. We investigated patient survivals between unplanned and planned HD in elderly patients and risk factors for mortality.
Results: Unplanned HD patients were older, had a higher dementia, congestive heart failure (CHF) and activities of daily living dependency, lower BMI, hemoglobin, albumin, hypertension and diabetes. However, there were no significant differences in the proportion of ischemic heart disease, cerebrovascular accident, in the hospitalization history prior to HD initiation between planned and unplanned HD. The proportions of catheter use at dialysis initiation and maintenance vascular access were significantly higher in the unplanned HD patients than in the planned HD patients. In Kaplan-Meier analysis, unplanned HD patients showed significantly lower patient survival rate than planned HD patients. In multivariate cox regression analysis, male, older age at dialysis initiation, lower body mass index, CHF, uncontrolled malignancy, lower activities of daily living dependency, hospitalization prior to HD, catheter use as a maintenance vascular access and lower serum albumin level were significantly associated with a higher risk of all-cause mortality.
Conclusions: In elderly ESRD patients, unplanned HD has a poor prognosis, and especially, catheter use as maintenance dialysis has a poor prognosis, so it is necessary to plan the appropriate vascular access in advance for the survival rate of elderly patients.
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