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논문분류	춘계학술대회 초록집
제목	DIFFERENT CLINICAL ASPECTS OF LUPUS NEPHRITIS IN YOUNG ADULT MALES : A CASE SERIES IN dr. SARDJITO YOGYAKARTA
저자	Ratna Damayanti
출판정보	2024; 2024(1):
키워드
초록	Systemic lupus erythematosus (SLE) is a systemic autoimmune inflammatory disease, which produce autoantibodies directed against nuclear elements and primarily affects women of reproductive age group. SLE in males are rare and lupus nephritis (LN) is a common and severe organ involvement which can manifest either at the onset or any time during the course of disease. In these paper we report a series of four male patients who presented at our centre with different clinical aspects and were diagnosed to have LN. First case was a 38-year-old man who previously treated as probable Ig A nephropathy since 2017 in Japan with losartan 12,5 mg once daily, he came to our centre in september 2021 with hematuria, increased creatinine level, positive ANA IF test result and kidney biopsy suggestive of LN class II. Second case was a 19-year-old man who diagnosed since 2022 with nephrotic syndrome, frequently relapsed and dependent steroid. His kidney biopsy suggestive of LN class III, focal lupus nephritis. Third case was a 33-year-old man who presented with nephrotic syndrome, ascites and pleural effusion. Laboratory testing show positive ANA IF test result with kidney biopsy suggestive lupus nephritis class III. Fourth case was a 35-year-old man who initially presented with uncontrolled hypertension followed by nephritic syndrome. Laboratory test results show positive ANA IF test result and decreased C3. His kidney biopsy suggestive of lupus nephritis class IV, diffuse proliferative nephritis. All patients were treated with immunosupressive drugs with various renal response. These cases highlights the difficulty of diagnosis and treatment of lupus nephritis.
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