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논문분류	춘계학술대회 초록집
제목	CORRELATION BETWEEN ESTIMATED GLOMERULAR FILTRATION RATE (eGFR) AND LEFT ATRIAL FUNCTION IN PATIENT WITH PRADIALYTIC CHRONIC KIDNEY DISEASE
저자	Dian Pritasari Jeger
출판정보	2024; 2024(1):
키워드
초록	Objectives: Chronic kidney disease (CKD) is defined by decrease in renal function shown by eGFR less than 60 mL/min/1,73 m2, or present of markers of kidney damage, or both, at least 3 months, regardless of the underlying cause. One of CKD complication is cardiovascular disease (CVD). Left atrial abnormalities, including structural and functional abnormalities, and left atrial volume increment, are independent prognostic factors of end-stage CKD. Echocardiographic parameters related to left atrial function and well-validated use are Left Atrial Volume Index(LAVI), Left Atrial Ejection/Emptying Fraction (LAEF), and Left Atrial Pressure (LAP). Methods: This was an analytical cross-sectional study. Subjects were recruited with consecutive sampling technique in Prof. Dr. I.G.N.G Ngoerah General Hospital, Denpasar during the period 2019-2020. The eGFR value was calculated by entering the serum creatinine value into the CKD-EPI formula. Evaluation of left atrial function using Philips Epiq 5Cechocardiography. LAVI, LAEF, and LAP values were measured by two observers blindly and independently. Results: There were 40 subjects with pradialytic CKD of 28 men (70%) and 12 women (30%). The mean creatinine value was 4 ± 1 mg/dL and the eGFR value was 18 ± 11 mL/min/1.73 m2. While the mean value of echocardiographic parametersobtained LAVI 23 ± 10 mL/m2, LAEF 53 ± 15%, and LAP 13 ± 5 mmHg. In this study, there was a correlation between eGFR and LAVI (r= -0,452; R2=20,4%; p= 0,003), no correlation between eGFR and LAEF (r= 0,266; R2=7,1%; p=0,097), and there was a correlation between eGFR and LAP in pradialytic CKD patient (r= -0,511; R2=26,1%; p=0,001). Conclusions: There was a correlation between eGFR and LAVI in pradialytic CKD patient. There was also a correlation between eGFR and LAP in pradialytic CKD patient. Age and LVMI also affect LAVI in pradialytic CKD patients.
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