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논문분류	춘계학술대회 초록집
제목	SOFA score at the time of CRRT initiation predicts the mortality of patients with acute kidney injury
저자	Donghui Shin
출판정보	2024; 2024(1):
키워드
초록	Objectives: Technological advances including continuous renal replacement therapy (CRRT) have improved the survival rates of critically ill patients with acute kidney injury (AKI). Nevertheless, accurately assessing patient severity and predicting prognosis are urgently needed. Here, we aim to investigate the clinical factors predicting mortality. Methods: Clinical and laboratory data of a total of 102 patients with AKI requiring CRRT were reviewed retrospectively. The data were collected at the visit to emergency room or at the time of CRRT initiation. In addition to routine data, we calculated sequential organ failure assessment (SOFA) score to estimate patient's severity. Results: The overall mortality rate was 74.5 %. Mann-Whitney U test showed that non-survivors had a longer time to CRRT initiation (136.5 vs. 74.5 h, p = 0.026), more red blood cell transfusions (2.0 vs. 1.0 units, p = 0.020), lower albumin levels (2.5 vs. 2.8, p = 0.006), and higher SOFA scores (14.0 vs. 12.0, p = 0.002) than survivors. Multivariable regression test showed that the SOFA score at the time of CRRT initiation was significantly associated with mortality (odds ratio = 1.234, p = 0.006) (Figure 1). In the receiver operating characteristic curve analysis, the SOFA score had an area under the curve of 0.7, demonstrating predictive validity for mortality (p = 0.002), and a SOFA score of 14.5 or higher strongly predicted mortality (Figure 2). Conclusions: This study indicates that the SOFA score at the time of CRRT initiation is a valid predictive model for mortality in critically ill patients with AKI requiring CRRT. “This abstract was also submitted for the (2023 APAC) congress. By submitting the abstract to APCN & KSN 2024, abstract authors declare that re-submitting the abstract is permitted by the organizers of the previous meeting”
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