| 초록 |
Objectives: To examine the effect of smoking on kidney function in Acute Coronary Syndrome (ACS) patients Methods: A retrospective cohort study design was conducted on data obtained from the medical record of ACS patients at Wahidin Sudirohusodo Hospital, Makassar. Results: Research conducted on 293 subjects which consists of 227 (77.5%) men and 66 (22.5%) female. The largest ACS group was IMA-EST with 134 (45.7%) subjects. The risk factors for diabetes mellitus (DM) and hypertension were 93 (31.7%) and 173 (59.0%) subjects, respectively. Total subjects who smoked were 151 (51.5%) subjects. In the group with estimated GFR 60 ml/min/1.73 m2 or less, there were 108 (67.1%) subjects were smokers and 53 (32.7%) were non-smokers. On the other hand, in the group with estimated GFR > 60 ml/min/1.73 m2, 43 (32.6%) subjects were smokers and 89 (67.4%) were non-smokers. The correlation was tested with Chi-square test, and it was statistically significant (p=0.000). If the risk of ACS subjects is calculated, smokers have a 4.21 times risk of developing CKD (eGFR 60 ml/min/1.73 m2) compared to non-smokers. Conclusions: Smoking increases the risk of decreased kidney function status (CKD incidence) in ACS subjects |