대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	Predicting risk factor of worsening kidney function in elderly Veteran population according to glycemic status
저자	Jin Seon Jeong
출판정보	2024; 2024(1):
키워드
초록	Objectives: Diabetes mellitus is major cause of chronic kidney disease. Limited data relating risk factors for kidney disease across patients with or without diabetes. We aim to investigate risk factors to predict worsening kidney function in elderly veteran population with according to glycemic status. Methods: In this retrospective study, a total of 1665 patients who measured serum glucose and albumin level between January 2016 and May 2021 were included. We categorized patients according to glycemic status as three groups – normoglycemia, impaired fasting glucose and diabetes populations. We used Kaplan-Meier to plot the survival curve. The hazard ratios (HRs) of renal outcome (i.e., a 50% or more decrease of the estimated glomerular filtration rate) were calculated after using Cox regression model. Cox proportional hazards model was used to explore risk factors affecting the progression of CKD. Results: During the median follow-up period of 3.5 years (maximum 6.0 years), the events of renal outcome occurred in 174 patients. The mean age of patients at enrolled was 76.2±9.2 years, 85% was male. Hypoalbuminemia (HR, 1.83, [95% CI 1.14-2.93]; P=0.012), hyperuricemia (HR, 1.02, [95% CI 1.10-1.17], P=0.019) and urine albumin to creatinine ratio (uACr, A3) (HR, 5.6 [95% CI 2.85-11.18], P<0.001) were risk factors for renal function decline in overall population. In diabetes population, hypoalbuminemia (HR, 2.24, [95% CI 1.28-3.91], P=0.005), hyperuricemia (HR, 1.10, [95% CI 1.00-1.20], P=0.043) and uACr (A3) (HR, 7.98, [95% CI 3.06-20.8], P<0.001) were risk factors of renal progression. In patients with impaired fasting glucose, only uACr(A3) (HR, 4.14, [95% CI 1.20-14.38], P=0.025) was a risk factor of renal progression. Conclusions: Serum albumin, uric acid and uACr may be needed to predict the risk of worsening kidney function with diabetes. Higher uACr is also a risk factor in prediabetes.
원문(PDF)	PDF 원문보기

목록

위로가기