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논문분류	춘계학술대회 초록집
제목	Relationship between high serum calcium phosphate levels and acute kidney injury during hospitalization
저자	Ussanee Boonsrirat
출판정보	2024; 2024(1):
키워드
초록	Objectives: An excess calcium phosphate (CaPO4) level appears to be a risk factor for acute kidney injury (AKI) development. Although several data show this relationship, few data on patients who were hospitalized are available. Thus, this study aimed to evaluate the association of corrected serum CaPO4 levels with the risk of development of in-hospital AKI. Methods: This large retrospective cohort study enrolled adult patients whose serum calcium, phosphate, and albumin levels within 24 hours of admission are available. CaPO4 levels were categorized into ≤ 27 and > 27 mg2/dL2. Piecewise regression analysis was performed using these cutoff values of CaPO4 levels. The odds ratios (ORs) for in-hospital AKI and in-hospital mortality of both groups were identified. Results: A total of 2,119 patients were included. The incidence rates of AKI in patients with CaPO4 levels ≤ 27 and > 27 mg2/dL2 were 9.6% and 10.9%, respectively. The bilinear association pattern between the corrected CaPO4 level and in-hospital AKI showed the lowest risk of AKI at 27 mg2/dL2. Piecewise regression analysis demonstrated that the CaPO4 level, which is further different from the cutoff >27 mg2/dL2 was associated with in-hospital AKI with OR of 1.029 (95% CI 1.013–1.045) and in-hospital mortality with OR of 1.025 (95% CI 1.010–1.039) for every increase in CaPO4 level by 1 mg2/dL2. Conclusions: The elevation of the CaPO4 level increased the risks for both in-hospital AKI and in-hospital mortality.
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