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논문분류	춘계학술대회 초록집
제목	Clinical Outcomes for Newly Diagnosed Diabetes Patients in Korea: A National Health Insurance Data
저자	Samel Park
출판정보	2024; 2024(1):
키워드
초록	Objectives: Diabetes mellitus (DM) is associated with multiple severe complications, such as chronic kidney diseases (CKD). However, previous research has faced challenges due to the absence of accurate information regarding the initial diagnosis of type 2 DM. This study explores clinical outcomes in newly diagnosed type 2 DM patients, utilizing the extensive scope of the National Health Insurance Service (NHIS) data in Korea. Methods: This study identified patients with newly diagnosed DM, excluding those under 20 or over 80 years of age, with a history of atherosclerotic cardiovascular disease or kidney disease (eGFR < 60, albuminuria, or relevant ICD codes). Control individuals were age and sex-matched at a 1:4 ratio. The main outcomes measured were the incidence of ischemic stroke, myocardial infarction, heart failure, all-cause mortality, and end-stage kidney disease (ESKD) that initiated renal replacement therapy. Results: Out of 2,199,685 individuals, 439,937 were newly diagnosed with DM. Initial findings revealed significant increases in the risk (hazard ratio, 95% confidence interval) of ischemic stroke (1.93, 1.87 – 1.99), myocardial infarction (2.08, 1.99 – 2.18), heart failure (2.1, 2.07 – 2.22), all-mortality (1.28, 1.24 – 1.32), and ESKD (4.72, 4.11 – 5.43) respectively. Following adjustment for covariates, the adjusted hazard ratios for ischemic stroke, myocardial infarction, heart failure, all-cause mortality, and ESKD were 1.70 (95% CI: 1.63 – 1.77), 1.78 (95% CI: 1.68 – 1.89), 2.13 (95% CI: 2.04 – 2.22), 1.10 (95% CI: 1.06 – 1.14), and (3.89, 3.28 – 4.62), respectively. Conclusions: Our research demonstrated that individuals newly diagnosed with type 2 DM showed an increased risk of ischemic stroke, myocardial infarction, heart failure, all-cause mortality, and ESKD, reflecting findings across the entire Korean population.
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