대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	Clinical Profile of Post-Kidney Transplantation Hypertension in Children
저자	Budyarini Prima Sari
출판정보	2024; 2024(1):
키워드
초록	Objectives: Hypertension is one of the commonest complication among kidney transplantation (KTX) recipients. The prevalence of post-KTX hypertension in children ranges between 60-90%. It is an important risk factor for graft loss, cardiovascular outcome and mortality. Adequate antihypertensive drugs could improve longterm graft and patient survival. Methods: We conducted cohort retrospective study with total sampling of all KTX children in dr. Cipto Mangunkusumo National Hospital, Jakarta, Indonesia, from 2015 until 2022. Participants whose age 11-17 years old and previously undergone hemodialysis or peritoneal dialysis were followed for their blood pressure at day 1,7; 1,3,6,12 months post-KTX. Mann-Whitney test was performed to analyze the association between independent variables with hypertension during follow up. We also conducted Kruskal-Wallis test to analyze antihypertensive combination with outcome of hypertension in month-12. Results: 19/31 children undergone KTX were enrolled. 16/19 had hypertension in post operative day 1 and decrease in 3 until 6 months. 9 of 19 patients received antihypertensive for more than 6 months, while 5 patient didn’t received antihypertensive drugs. On bivariate analysis, related donor was protective factor towards hypertension after 1 and 6 month [1 month: RRs of 0,429; (CI95% 0,234-0,785); 6 months: RRs of 0,462; CI95% 0,257-0,830)]. Combination of calcium channel blocker (CCB) and beta blocker was associated with better hypertension improvement in month-12. Hypertension showed a decrease in trend during follow up from 84,2% to 27,8% after one year of KTX. Conclusions: Hypertension was found in post-KTX children up to 12 months and related donor was protective factor to hypertension. Combination of CCB and beta blocker brought beneficial effect on improvement of post-KTX hypertension in children.
원문(PDF)	PDF 원문보기

목록

위로가기