| 초록 |
Objectives: Worldwide, urinary tract infection (UTI) is considered a major public health issue and the second most common bacterial infection affecting individuals of various ages. The Global Research on Antimicrobial Resistance (GRAM)Project, conducted the first known long-term study to estimate the global consumption of antibiotics, which covered 204 nations from years 2000–2018. According to this estimation of the average daily dose, a significant increase of 46% in the global antibiotic consumption rate was observed throughout this period of time. Antibiotic resistance has become an indispensably alarming menace to the global community due to the misuse of antibiotics. Our main goal of conducting this study was to determine prevalence of pathogen and antibiotic susceptibilty. Methods: This study was conducted in outpatient department, at The Third Central Hospital. A cross-sectional study was carried out over 12 months (January to December 2023) with a focus on the identification of bacterial pathogens causing UTI and the evaluation of their antibiogram. We excluded culture negative specimen. In total, 681 culture positive urine samples were included and determined prevalence and antibiotic susceptibility . Antibiotic susceptibility was carried out following CLSI recommended guidelines. Results: Among them, 615 (90.3%) of the strains were isolated from female patients. By age, dominated age group was 46-65 (47.1%). The frequently identified isolates were Escherichia coli (57.7%), followed by ESBL producing E.Coli (8.5%) and Kocuria spp (7.4 %). Extended -spectrum beta -lactamases identified 8.8%, from which dominated E.Coli (8.5%). Conclusions: The highest percentages of resistance have been observed against tested antibiotics. We investigated that Gram-negative bacteria were the leading cause of UTIs where the predominant microorganism was E. Coli. In our study, the predominant isolated organisms responsible for UTI in Mongolia were E. coli, ESBL producing E.Coli and Kocuria spp. In conclusion, antibiotic resistance is increasing in Mongolia due to abusage of antibiotics. |