| 초록 |
Objectives: To study the incidence, causes ,staging and outcomes of AKI (acute kidney injury) in patients suffering from malignancy Methods: A total of 200 cancer patients with AKI admitted in Basavatarakam Indo American Cancer hospital, Hyderabad, India were studied. Results: Out of 200 patients in the study, 124 were males and 76 were females.Most of the patients are in 51 to 60 years age group(80 patients) and the mean age of the patients was 54.76 years.Bladder cancer was common malignancy seen in 24 patients, followed by breast cancer, lung cancer and AML seen in 20 patients.Multifactorial AKI was seen in 44 patients ,though each and every variant of malignancy has specific cause of AKI, sepsis was commonly seen in all types of malignancies.140 patients underwent conservative management for AKI without dialysis had complete recovery from AKI.60 patients received dialysis for AKI, of which 4 patients received hemoperfusion with HA-230 filter for methotrexate has completely recovered,8 patients with multiple myeloma underwent dialysis with theranova filter got completely recovered ,4 patients with multiple myeloma underwent dialysis with theranova was dialysis dependent.4 patients who underwent SLED for AKI has completely recovered,12 patients who underwent SLED for AKI were dialysis dependent and 4 patients who underwent SLED has expired.20 patients received CRRT for AKI and among them Oxiris filter was used in 4 members. Only 1 patient who received CRRT had complete renal recovery,4 patients were dialysis dependent and 15 patients who was on CRRT expired during hospital stay. Conclusions: Sepsis was the common cause of AKI in many cancer variants. More the severity of AKI was associated with more adverse out comes. All types of AKI like pre-renal, intrinsic renal and obstructive element was seen in patients with AKI in the background of malignancy. |