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논문분류	춘계학술대회 초록집
제목	Association of Weekend-to-Weekday Sleep Duration Ratio with Kidney Function
저자	Wanprapit Noree
출판정보	2024; 2024(1):
키워드
초록	Objectives: Short sleep duration is known to be associated with a decline in the eGFR in a large cohort of women. However, the association of Weekend-to-Weekday sleep patterns with eGFR in a nationally representative population remains unknown. The objective of this study is to examine the correlation between Weekend-to-Weekday sleep patterns and eGFR in the general population. Methods: A cross-sectional study was conducted using a population from the 2017-2020 National Health and Nutrition Examination Survey (NHANES). The questionnaire collected self-reported data on the participants' average sleep duration during weekends and weekdays. Their eGFR values were assessed, and the relationship between the weekend-to-weekday sleep duration ratio and eGFR was analyzed by multivariable linear regression analysis. Results: The study involved 9,693 adult participants, with a mean ± SD age of 50 ± 19 years and 51% being female. The mean ± SD estimated glomerular filtration rate (eGFR) was 104.73 ± 65.99 mL/min/1.73 m2. The mean ± SD of Weekday and Weekend sleep hours were 7.59 ± 1.68 hr and 8.26 ± 1.80 hr respectively. The study found a significant association between eGFR levels and the Weekend-to-Weekday Sleep Duration Ratio. If the sleep-duration ratio increases by 1, the eGFR level increases by 27.5 and 13.76 mL/min/1.73 m2 after adjusting for race, gender, and other factors (coefficients (95% CI); P-value = 27.25 (6.54, 47.95); 0.010 and 13.76 (8.85, 18.68); < 0.010, respectively). The severity of urine leakage was identified as an effect modifier with an increase association. Conclusions: The weekend-to-weekday sleep duration ratio was positively associated with eGFR in a general representative population. This study implies that full recovery sleep on the weekend after sleep-deprived weekdays may be able to preserve kidney function. Several factors, including other comorbidities and sleep environments on weekdays and weekends, may contribute to sleep quality and subsequently eGFR.
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