| 초록 |
Contrast-induced nephropathy (CIN) is one of the common causes of acute kidney injury (AKI), often presenting with a favorable prognosis, which makes it easily overlooked during diagnosis. The purpose of this study was to investigate the clinician's efforts to detect CIN after CM exposure and the prevalance of CIN. This study was conducted as a single-center, prospective, observational study and targeted patients hospitalized at GNUCH from July-2024 to December-2024. The study included adults aged 18 years or older with CKD who were exposed to CM through procedures such as CT or CAG. Exclusion criteria were pediatric patients, patients undergoing hemodialysis, those with AKI within the past three months. Creatinine levels were measured at two-time points: pre-exposure(P0), and within 48 hours post-exposure(P2). CIN was defined according to KDIGO guidelines. Among 44,853patients who underwent CT from March 2016 to June 2024 as outpatients of our hospital, 43,721(97.4%) did not have renal function evaluation within 72hours after CT, and 39,408(87.9%) did not have renal function evaluation within 7 days. A total of 182 participants were enrolled in the study, with a mean age of 73.25 ± 2.8 years; 56% were male. CIN was identified in 33 patients (18.1%). Among these, 23 patients(12.6%) had CKD stage 3, and 5 patients(2.7%) each had CKD stages4 and 5. CIN occurrence was significantly higher in patients using ARB(53.7% vs. 72.7%, p=0.046) and inotropic agents(4.7% vs. 18.2%, p=0.007). The occurrence of CIN can have a significant impact on renal function and prognosis, but most clinicians overlook it and do not perform laboratory tests after CM exposure. We should be aware that the incidence of CIN may be higher than expected, and we should make continuous efforts to preserve patients' renal function through early detection and treatment of CIN. |