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논문분류	춘계학술대회 초록집
제목	Fatty Kidney Is Associated With the Severity of Metabolic Dysfunction
저자	Kootae Park
출판정보	2025; 2025(1):
키워드	Metabolic syndrome, Computed tomography, Metabolic kidney disease, Ectopic fat, Metabolic syndrome severity score
초록	Metabolic syndrome severity score (MSSS) is an indicator for assessing severity of metabolic dysfunction. This study aimed to investigate the correlation between MSSS and attenuation of abdominal fats, and ectopic fat depots measured by computed tomography. This study analyzed the data of medication-naïve 358 participants (men, 70.9%) who underwent abdomino-pelvic computed tomography (APCT) imaging. MSSS was calculated based on metabolic parameters and divided into 3 groups according to the severity. We measured the attenuation of abdominal fats and ectopic fat depots including intramuscular, perivascular using APCT. Additionally. liver and kidney fat contents were assessed APCT attenuation. Higher MSSS was significantly associated with increased body fat percentage (p<0.05). MSSS was significantly higher in female (p=0.0024). There was no relationship between aging and MSSS (p=0.654). APCT based analysis revealed that increasing MSSS was significantly associated with decreasing attenuation of visceral peritoneal fat and kidney (p<0.05). In multiple regression analysis, visceral peritoneal fat attenuation (β=-0.2547, p<0.001) and kidney attenuation (β=-0.1529, p=0.0274) remained independently associated with MSSS. MSSS is strongly correlated with low attenuation in visceral peritoneal fat and kidney. These findings suggest that the quality of visceral fat and kidney fat infiltration is associated with increased metabolic abnormality in treatment naïve individuals.
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