대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	The Prognostic Value of Handgrip Strength on Survival in Hemodialysis Patients
저자	Kyungho Park
출판정보	2025; 2025(1):
키워드	Hemodialysis, Handgrip Strength, Muscle Mass, Survival, Bioimpedance Spectroscopy
초록	Patients undergoing hemodialysis experience significantly increased mortality risk, emphasizing the need for precise clinical assessments. Protein-energy wasting (PEW) contributes to muscle loss and frailty, which are closely linked to poor outcomes, including heightened mortality rates. As muscle mass declines, functional performance deteriorates, underscoring the importance of regularly evaluating both muscle quantity and functionality. Handgrip strength (HGS), a simple and effective measure of muscle strength, can serve as a valuable indicator of patient prognosis. This study examines the prognostic significance of HGS for survival among hemodialysis patients, exploring its relationship with muscle mass and body mass index (BMI). We conducted a retrospective cohort analysis of 408 dialysis patients (221 males, 187 females) assessed with bioimpedance spectroscopy (BIS) and HGS tests from March 2021 to August 2023. Variables collected included BIS measurements, HGS, dialysis-related information, age, complete blood counts, biochemical profiles, mortality data, and CONUT scores. Cox proportional hazards analysis indicated that lean tissue index (LTI) (HR 3.30, 95% CI 1.75–6.19), BMI (HR 2.65, 95% CI 1.17–6.01), and HGS (HR 4.22, 95% CI 2.05–8.70) significantly predicted survival across the entire cohort. In gender-specific analyses, male survival was significantly predicted by both LTI (HR 4.81, 95% CI 1.89–12.23) and HGS (HR 5.45, 95% CI 2.18–13.61). Among female patients, HGS strongly predicted survival (HR 6.01, 95% CI 2.42–14.94), and LTI also showed significance (HR 3.22, 95% CI 1.24–8.40, p = 0.017). In multivariate analyses adjusted for age, diabetes mellitus, hypertension, BMI, fat tissue index, LTI, serum albumin, C-reactive protein, and CONUT score, HGS independently remained a significant predictor for survival, especially among female dialysis patients (HR 2.77, 95% CI 1.00–7.65, p = 0.049). Handgrip strength is a critical prognostic indicator for survival among hemodialysis patients, particularly in females, independent of muscle mass and BMI.
원문(PDF)	PDF 원문보기

목록

위로가기