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논문분류	춘계학술대회 초록집
제목	Pregnancy-Related AKI Treated With Dialysis: Characteristics and Outcomes Explored.
저자	Abhilash Chandra
출판정보	2025; 2025(1):
키워드	Dialysis, AKI, pregnancy, recovery, necrosis
초록	To investigate the incidence and outcomes of severe cases of dialysis requiring AKI in pregnant patients This retrospective study analyzed the data of dialysis-requiring pregnancy-related AKI admitted to Nephrology over 4 years (January 2020- December 2024). Postpartum acute kidney injury (PPAKI) was defined as AKI diagnosed from the time of childbirth to 6 weeks post-delivery, following the KDIGO guidelines. Recovery was categorized as: - Complete recovery: normal serum creatinine (<1.0 mg/dL) or a previously known baseline, with no proteinuria at the end of 3 months - Partial recovery: improved renal function with dialysis independency, but serum creatinine not returning to baseline or normal range - Non recovery: patients requiring dialysis at the end of 3 months Exclusion criteria: Patients with underlying chronic kidney disease and pre-pregnancy hypertension Out of 16,584 pregnancies, 126 (0.76%) were complicated by Acute Kidney Injury (AKI). Only 13 of the 126 women had a preexisting comorbidity. The study included 52 patients with an average age of 24±7 years. The average serum creatinine level upon presentation was 6.3±1.65 mg/dl. (Table 1) 2 patients, or 3.8%, did not survive, and 15 patients, or 28.84%, remained dependent on dialysis three months post-delivery. Interestingly, there was no significant difference in the incidence of low birth weight, small for gestational age, or preterm birth compared to those without AKI (15.6% versus 13.1%; p value=0.45). Acute cortical necrosis was reported in 12(23.06%) cases (Table 2). Among patients who did not recover from AKI, thrombotic microangiopathy was the cause in 5 cases, acute cortical necrosis in 9 cases, and severe acute tubular necrosis in 1 case. Partial recovery was observed in 12 subjects, accounting for 23.1% of cases. Pregnant individuals with AKI who undergo dialysis face a higher likelihood of experiencing non-recovery or only partial recovery of their renal function
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