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논문분류	춘계학술대회 초록집
제목	Association of Prognostic Nutritional Index (PNI) and the 30-Day Mortality in ICU Patients With Acute Kidney Injury: A Retrospective Cohort Study
저자	Christen Marie Talosig
출판정보	2025; 2025(1):
키워드	Acute Kidney Injury, PNI, Malnutrition , Mortality Risk
초록	To determine the association between Prognostic Nutritional Index and 30-day mortality in ICU patients with Acute Kidney Injury We conducted a retrospective cohort study involving adult patients with Acute Kidney Injury admitted to the Medical Intensive Care Unit from June 2021 to June 2023. Demographic and clinical data were collected by reviewing the electronic medical records. Patients were grouped as either expired or survived. The use of PNI score was assessed in all patients. Univariate and multivariate analysis were done to determine the association of PNI score and 30-day all-cause mortality among AKI patients at the medical ICU The study included 209 patients, of whom 138 (66%) died within 30 days of ICU admission, and 71 (34%) who survived. Most patients (68.9%) had a PNI score of < 35 and were classified as having a severe risk for malnutrition, 13.9% were under moderate risk, and 17.2% were under normal risk for malnutrition. The mean SOFA and GCS scores were 8.0 and 9.6, respectively. There was an association between the PNI score and all-cause mortality among AKI patients in the ICU in the unadjusted model (ORC = 2.2 (1.2 to 4.0), p = 0.013). However, after multiple predictor logistic regression analysis, AKI nonresolution (ORA = 10 (4.5 to 23), p = 0.001), SOFA (ORA = 1.3 (1.1 to 1.5), p = 0.001), and GCS (ORA = 0.8 (0.6 to 1.0), p = 0.015) scores remained significantly associated with 30-day all-cause mortality. Prognostic Nutritional Index is a potential predictor of 30-day mortality among ICU patients with AKI but should not be used in isolation but rather in conjunction with other clinical parameters in risk stratification such as SOFA and GCS score. Further prospective studies are needed to confirm the association between PNI and short term mortality in patients with AKI.
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