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논문분류	춘계학술대회 초록집
제목	Management of Early Onset Acute Fatty Liver of Pregnancy With Double Plasma Molecular Adsorption System (DPMAS) in a 36-Year-Old Filipino Woman: A Case Report
저자	Karren Mae Plete
출판정보	2025; 2025(1):
키워드	Acute Fatty Liver of Pregnancy, DPMAS, hemoperfusion, Case report, Second trimester
초록	A single case study approach was adopted, focusing on a 36-year-old Filipino female patient (G3P1) diagnosed with Acute Fatty Liver of Pregnancy (AFLP) at 15 6/7 weeks of gestation. Inclusion criteria involved confirmed AFLP diagnosis based on presenting symptoms and laboratory findings. A single case study approach was adopted, focusing on a 36-year-old Filipino female patient (G3P1) diagnosed with Acute Fatty Liver of Pregnancy (AFLP) at 15 6/7 weeks of gestation. Inclusion criteria involved a confirmed AFLP diagnosis based on presenting symptoms and laboratory findings. patient underwent 3 sessions of DPMAS for 3 consecutive days. The management of the patient involved administering hemoperfusion using the Dual Plasma Molecular Adsorption System (DPMAS), which resulted in significant clinical improvements. Within a few days of the intervention, liver function tests demonstrated a marked normalization of liver enzymes, with decreased transaminases and bilirubin levels. The patient reported a resolution of jaundice symptoms, evidenced by a gradual return to normal skin coloration and reduced scleral icterus. Additionally, there was a notable alleviation of nausea and abdominal pain shortly after the treatment, highlighting the efficacy of hemoperfusion in addressing Acute Fatty Liver of Pregnancy. This case stresses the need to recognize AFLP in early pregnancy, despite its usual late occurrence. Early detection and timely multidisciplinary intervention, including DPMAS hemoperfusion, can yield positive outcomes for both mother and fetus. The management of this case illustrates the effectiveness of DPMAS in treating severe liver dysfunction during pregnancy.
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