| 초록 |
Malnutrition and inflammation are crucial risk factors impacting the prognosis of hemodialysis (HD) patients. The Malnutrition Inflammation Score (MIS) evaluates the nutritional status and inflammation levels in these patients, closely linked to increased morbidity and mortality. This study aims to investigate the sensitivity of various nutritional status parameters in predicting the Malnutrition Inflammation Score (MIS) among hemodialysis (HD) patients, to improve early identification and management of at-risk individuals. This observational cross-sectional study was conducted at the dialysis unit of Sardjito General Hospital, Yogyakarta, in October 2024. A total of 59 MHD patients undergoing dialysis twice a week were involved. Collected data included age, gender, hemodialysis vintage, Dialysis Malnutrition Score (DMS) form, anthropometric data (BMI, MUAC, total fat percentage, visceral fat), handgrip strength (HGS), and biochemical data (BUN, creatinine, total cholesterol, HDL-C, LDL-C, triglycerides, albumin, TIBC). MIS ranges from 0-30 and is categorized as malnutrition with a score of ≥5. Chi-square test (p<0.05) and diagnostic test (Sensitivity [Se], Specificity [Sp], Maximum Test Sensitivity Plus Specificity Threshold [MSS]) were used in data analysis. The prevalence of malnutrition based on MIS is 59.3%. There is a significant correlation between MIS and MUAC, %Total fat, HGS, creatinine, total cholesterol, LDL-C, triglycerides, and albumin (p<0.05). This indicates that MHD patients with higher MIS scores tend to have worse outcomes in the nutritional status parameters mentioned above. The diagnostic test results, categorized based on the highest MSS, include the following values: DMS (142.9), triglycerides (136.79), LDL-C (134.17), total cholesterol (132.38), HGS (132.11), and creatinine (129.29). DMS and HGS are more practical parameters for evaluating nutritional and inflammatory status in hemodialysis patients, as they do not necessitate laboratory testing. |