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| 논문분류 | 춘계학술대회 초록집 |
|---|---|
| 제목 | Hydrogen Sulfide and Homocysteine Transsulfuration Pathway in the Progression of Kidney Fibrosis |
| 저자 | Hee-Seong Jang, Jee In Kim, Sang Jun Han, Kwon Moo Park |
| 출판정보 | 2013; 2013(1): |
| 키워드 | 황화수소, 섬유화, 활성산소/Hydrogen sulfide, Fibrosis, Oxidative stress |
| 초록 | Hydrogen sulfide (H2S) produced by cystathionine β-synthase (CBS) and cystathionine γ-lyase (CSE) in the transsulfuration pathway of homocysteine has diverse role in pathophysiological condition. The role of H2S in kidney fibrosis remains to be defined despite involvement of hyperhomocysteinemia in kidney fibrosis. Here, we investigated the role of H2S and its acting mechanism in unilateral ureteral obstruction (UO)-induced kidney fibrosis in mice. |
| 원문(PDF) | PDF 원문보기 |
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