대한신장학회

간행물 검색

현재 페이지 경로

논문분류	춘계학술대회 초록집
제목	Oleanolic Acid Attenuates Renal Interstitial Fibrosis in Unilateral Ureteral Obstructive Nephropathy by Facilitating Nuclear Translocation of Nrf2
저자	Sungjin Chung, Hye Eun Yoon, Soo Jeong Kim, Sung Jun Kim, Eun Sil Koh, Cheol Whee Park, Yoon Sik Chang, Seok Joon Shin
출판정보	2013; 2013(1):
키워드	신장 섬유화, 산화 스트레스, 항산화제/ Renal fibrosis, Oxidative stress, Oleanolic acid
초록	Renal interstitial fibrosis is a common final pathological process in the progression of renal disease. This is primarily due to oxidative stress, which contributes to renal inflammation and fibrosis. Nuclear factor-erythroid-2-related factor 2 (Nrf2) is known to coordinate induction of genes that encode antioxidant enzymes. We investigated the effects of oleanolic acid, a known Nrf2 activator, on oxidative stress-induced renal inflammation and fibrosis.
원문(PDF)	PDF 원문보기

간행물 검색