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논문분류	춘계학술대회 초록집
제목	Oleanolic Acid-induced Nrf2 Activation Attenuates Renal Oxidative Stress and Tubulointerstitial Fibrosis in Chronic Cyclosporine Nephropathy
저자	Yu Ah Hong1, Min Young Kim2, Ji Hee Lim2, Eun Nim Kim2, Seok Joon Shin2, Cheol Whee Park2, Sungjin Chung2
출판정보	2013; 2013(1):
키워드	Nrf2, Oxidative stress, Cyclosporine 신병증
초록	Cyclosporine (CsA)-induced kidney injury is characterized by renal dysfunction with inflammatory cell infiltrations, apoptosis and fibrosis. Nuclear factor erythroid-2-related factor-2 (Nrf2) is known to confer protection against tissue injury by orchestrating antioxidant and detoxification responses to oxidative stress. This study investigated whether upregulation of Nrf2-depedent antioxidative signaling by OA would attenuate renal inflammation fibrosis in CsA-induced kidney injury.
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