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| 논문분류 | |
|---|---|
| 제목 | Modulation of Endothelial function Attenuates Kidney Fibrosis by Regulation of Soluble Epoxide Hydrolase |
| 저자 | Jung Pyo Lee1, Seung Hee Yang3, Jin Hyuk Kim1, Do Hyung Kim4, Hee-Yoon Lee5, Joo-Youn Cho4, Yoon Kyu Oh1, Yon Su Kim2, Chun Soo Lim1 |
| 출판정보 | 2013; 2013(1): |
| 키워드 | 내피세포, 신섬유화, 에폭사이드 하이드롤라아제/ Endothelial cell, Kidney fibrosis, Soluble epoxide hydrolase |
| 초록 | Soluble epoxide hydrolase (sEH) in endothelial cells catalyses the degradation of epoxyeicosatrienoic acids (EETs), which may act as vasoactive agents to control vascular tone. Kidney fibrosis is the final common pathway for most progressive kidney diseases. Here we show that kidney fibrosis was reduced by regulation of sEH activity. |
| 원문(PDF) | PDF 원문보기 |
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