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논문분류	춘계학술대회 초록집
제목	Posttransplant Outcomes and Risk Factors in Diabetic Kidney Transplant Recipients
저자	Nara Shin1, Ryu HyunJin1, Sunwha Lee1, Su Mi Lee1, Hajeong Lee1, Jung Pyo Lee2, Yon Su Kim1
출판정보	2013; 2013(1):
키워드	당뇨병성 신증, 이식 후 예후/ Diabetic nephropathy, Transplant outcomes
초록	Background: Diabetic nephropathy (DN) is not the leading population in the recipients for kidney transplant, although DN is the most common cause of end-stage renal disease. Here, we identified the outcomes of kidney transplant in patients with DN and analyzed the risk factors affecting outcomes. Methods: A total of 705 consecutive Korean recipients who underwent kidney transplantation at Seoul National Hospital between 1997 and 2011 were enrolled. Graft failure and biopsy-proven acute rejection (BPAR) were reviewed with focusing on the patients with diabetic nephropathy. Results: Compared with non-diabetic nephropathy group, there were more male (p=0.008), ischemic heart disease(p<0.001), and cereberovascular accidents (p=0.041) in DN group. DN increased the risk of graft failure by 2.58-fold(95% confidence interval [CI] 1.28-5.21) after adjusting for other risk factors. In addition, DN was a significant risk factor for BPAR (odds ratio [OR] 1.75, 95% CI 1.09-2.80, p=0.020). On the subgroup, deceased donor kidney transplant and longer renal replacement therapy increased the risk of graft failure. However, glycemic control did not affect the graft outcomes. Conclusion: Diabetic kidney transplant recipients showed inferior outcomes with higher rates of graft failure and BPAR. Customized and intensified approach should be instituted for the recipients with DN.
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