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논문분류	춘계학술대회 초록집
제목	The Renal Outcome after Liver Transplantation in Fulminant Hepatitis A with Acute Kidney Injury; Comparison with Hepatorenal Syndrome
저자	Jae-yoon Park1, Jung Pyo Lee2, Geum-Youn Gwak3, Jong Man Kim4, Hyung Jung Oh5, Nam-Joon Yi6, Kyung-Suk Suh6, Dong Ki Kim1, Chun Soo Lim2, Yon Su Kim1
출판정보	2013; 2013(1):
키워드	급성신손상, A형간염, 간이식/ Acute kidney injury, Acute hepatitis A, Liver transplantation
초록	Background: Liver transplantation (LT) is the treatment of choice for hepatorenal syndrome (HRS). However the outcome of LT is not well established in recently increasing acute hepatitis A accompanied by acute kidney injury (AKI). We, therefore, investigated the outcomes of LT in patients with AKI by acute hepatitis A comparing to those of patients with HRS by other causes. Methods: We reviewed 1940 adult recipients who underwent LT consecutively at three Korean liver transplantation centers from 2005 to 2012. A total of 20 acute hepatitis A with AKI patients (HAV group) were compared with 76 patients with HRS by other causes (HRS group). Results: There was no difference of model for end-stage liver disease score between two groups. Pretransplant estimated glomerular filtration rate (eGFR) was lower in HAV group than in HRS group (20.6±12.7 vs. 28.2±12.8 mL/min/1.73m2, p=0.021). Posttransplant patients’ and grafts’ survival rate were similar. More patients in HAV group needed posttransplant hemodialysis than in HRS group (65.0% vs. 38.2%, p=0.043). However, eGFR has been maintained significantly higher in HAV group since posttransplant 2 month (p<0.05). There was no patient who needed longterm renal replacement therapy in both groups. Conclusion: Pre- and immediate posttransplant kidney functions of HAV group were worse than those of HRS group. However, posttransplant longterm renal outcome could be better in HAV group.
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