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논문분류	춘계학술대회 초록집
제목	Vancomycin-induced Acute Generalized Exanthematous Pustulosis in a Patient on Peritoneal Dialysis
저자	Mun Ju Hwang, Seok Hui Kang, Eun Woo Choi, Yo Han Chung, Hi Jung Lee, Kei Lim Shin,Kyu Hyang Cho, Jong Won Park, Kyung Woo Yoon, Jun Young Do
출판정보	2013; 2013(1):
키워드	반코마이신, 발진성 농포, 복막투석/Vancomycin, Exanthematous pustulosis, Peritoneal dialysis
초록	Acute generalized exanthematous pustulosis (AGEP) is an uncommon, reactive lesion which is characterized by an acute onset of monomorphic, small sterile pustules on an erythematous background. We present a case of vancomycin- induced AGEP in a patient on peritoneal dialysis (PD). A 39-year-old female on PD visited to out hospital for exit site discharge. Five months previously, she had been diagnosed with end-stage renal disease owing chronic glomerulonephritis. She had received PD as renal replacement therapy. The exit site infection poorly responded to ciprofloxacin. Result from the culture showed isolation of methicillin-resistant Staphylococcus epidermidis and the patient received intravenous vancomycin 1g/week. Two week later she consulted due to the presence of cutaneous rash in whole body without fever. A skin biopsy consisted with acute generalized exanthematous pustulosis. The patient discontinued vancomycin and received prednisolone (20mg/day), but the skin lesion did not improved. Viral pneumonia developed during steroid therapy and steroid was stopped. Ten days later, viral pneumonia and the skin rash regressed and were followed by desquamation.
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