| 저자 |
Kang Ryun Moon, Ye Jin Kim, Ki Dae Kim, Sarah Chung, Dae Eun Choi,Ki Ryang Na, Kang Wook Lee, Young Tai Shin, Jin Soo Kim |
| 초록 |
Introduction: Sclerosing encapsulating peritonitis (SEP) is
a rare but a life-threatening complication of peritoneal
dialysis.
The pathophysiology of SEP is excess fibrosis, which
induces an encasement of the small bowel, resulting
clinically
in bowel obstruction and malnutrition. Although
glucocorticoid and tamoxifen have been used for the
treatment of
SEP, some patients complicated with prolonged bowel
obstruction need surgical treatment such as laparotomy
and
enterolysis. But mortality risk of such surgical treatment is
known to be very high. Here we report a case of SEP
which appeared one month after switching to hemodialysis
from peritoneal dialysis, successfully treated with
laparotomy
and enterolysis.
Case: A 60-year-old female came to our hospital with
nausea, vomiting, abdominal distension for 3days.
Peritoneal
dialysis was started due to diabetic end-stage renal
failure 10 years ago. She has suffered from seven times of
peritonitis
during 10 years of peritoneal dialysis. Blood pressure was
113/50 mmHg, Heart rate 103, respiratory rate 20,
body temperature 36.7℃ at the time of admission. Her
consciousness was clear but complained of generalized
weakness.
The complete blood counts showed hemoglobin 7.9 g/dl,
WBC 26,200 cells/μL, and platelet 329,000/μL. The
results of blood chemistry were as follows: AST 17IU/L,
ALT 6IU/L, total protein 5.9 g/dL, albumin 2.1 g/dL, BUN
13.2 mg/dL, creatinine 03.72 mg/dL. Serum sodium,
potassium and chloride were 141 mEql/L, 3.3 and 104
mEq/L.
C-reactive protein was 16.7 mg/dL. On arterial blood gas
analysis, pH was 7.43, PaO2 68 mmHg, PaCO2 41 mmHg,
bicarbonate 17.2 mEq/L and O2 saturation 94%.
Abdominal pelvic CT showed typical finding of SEP as
massive ascites and peritoneal thickening and
encapsulating
bowel loops like cocoon. She took prednisolone and
tamoxifen for 8 weeks. Finally, she got partial
peritonectomy
and total enterolysis because there was no improvement
of ileus and malnutrition. She recovered dramatically after
surgery. |