대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	Living Donor Kidney Transplantation from HBsAg (+) Donor to HBsAg (-) Recipient
저자	Sung Hyun Son1, Jin Min Kong1, Hyukyong Kwon1, Joon Heun Jeong2,Dong Ryul Lee3, Jungmyung Ahn3
출판정보	2013; 2013(1):
키워드	HBs Ag 양성 공여자, HBs Ag 음성 수혜자, 신이식/HBs Ag positive donor, None HBs Ag recipient, Transplantation
초록	Aims: HBsAg positivity is currently regarded as a contraindication of kidney donation to HBsAg negative patients. We developed a protocol that enables transplantation from an HBsAg (+) donor to an HBsAg (-) recipient. Methods: Transplant candidates without protective titer (≥10 mIU/ml) of anti-HBs antibody were given hepatitis B vaccination to develop protective level of antibody. Viral load of donors was reduced by entecavir to be undetectable by real time PCR before transplantation. Recipients were also given entecavir before and during 3 months after transplantation for prophylaxis. Hepatitis B immune globulin was injected to recipients intravenously in the morning of transplant day. Results: Six living donor kidney transplantations in 5 patients from HBsAg (+) donor to HBsAg (-) recipient were performed. In 5 transplantations, recipient had protective titer of antibody at initial presentation. One patient had low titer of anti-HBs (7mIU/ml), which was raised by hepatitis B vaccine to protective level (15mIU/ml) before transplantation. All the recipients had undetectable HBV DNA after transplantation and remained HBsAg (-)/anti-HBs (+) during the median follow up of 21 (4-40) months. Conclusions: Kidneys from HBsAg (+) living donors can be safely transplanted to HBsAg (-) recipients.
원문(PDF)	PDF 원문보기

목록

위로가기