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논문분류 춘계학술대회 초록집
제목 Membranous Nephropathy with Superimposed Rapidly Progressive Crescentic Glomerulonephritis and Renal Vein Thrombosis
저자 Hyun Kyung Kim, Min Su Kim, Hye Ryun Jang, Wooseong Huh,Dae Joong Kim, Ha Young Oh, Yoon Goo Kim
출판정보 2013; 2013(1):
키워드 막성신병증, 급성 반월상 사구체 신염, 신정맥 혈전증/Membranous nephropathy, RPGN, Renal vein thrombosis
초록 There have been only sporadic reports of membranous nephropathy (MN) evolving into acute crescentic rapidly progressive glomerulonephritis (RPGN). Here we report a case of rapidly progressive glomerulonephritis accompanied with renal vein thrombosis which developed in a patient with membranous nephropathy. A 38-year-old male with membranous nephropathy hospitalized due to right flank pain. A computed tomography scan revealed right renal vein thrombosis and creatinine level was 1.34 mg/lL. Therapeutic anticoagulation therapy was started with warfarin for renal vein thrombosis. The patient returned for follow-up after 6 days. His serum creatinine level greatly increased to 6.36 mg/dl and potassium level was 7.6 mg/dl. One session of emergent hemodilaysis and kidney biopsy was performed. A Kidney biopsy revealed acute crescentic glomerulonephritis and monthly cyclophosphamide was infused intravenously with oral prednisolone during three months. Serum creatinine level normalized to 0.93mg/dl and cyclophosphamide switched to mycophenolate. So we report a rare case of rapidly progressive glomerulonephritis with renal vein thrombosis in membranous nephropathy patient.
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