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논문분류	춘계학술대회 초록집
제목	Monoclonal Gammopathy of Undetermined Significance Presenting with Severe Renal Failure
저자	Ye Na Kim, Sangeon Gwoo, Son Ok Lee, Ho Sik Shin, Yeon Soon Jung, Hark Rim
출판정보	2013; 2013(1):
키워드	단클론성 감마병증, 급성신손상, 혈액투석/MGUS, Acute Kidney Injury, HD
초록	We experienced a case of 73-year-old man who denied any underlying conditions and presented with acute kidney injury and proteinuria. Laboratory data indicated renal failure and abnormal paraprotein in the serum and urine. This patient was diagnosed with monoclonal gammopathy and renal failure due to kappa and lambda light-chain deposition in the glomerular basement membrane. A renal biopsy indicated acute tubular necrosis and a cast in the renal tubule. The plasma cell counts were normal on bone marrow biopsy. After 2 months, he received maintenance hemodialysis for the irreversible renal failure. Clinical features as well as kinetic and immunological studies were consistent with the diagnosis of monoclonal gammopathy of undetermined significance. The findings of this case suggest that renal failure complicating monoclonal gammopathy of undetermined significance is not related to its malignancy.
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