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논문분류	춘계학술대회 초록집
제목	Diffusion-weighted MRI Compared to CT of Exercise-induced Acute Renal Failure (ALPE)
저자	Joon-Yeop Lee1, Jung Ho Seo1, Kyoung Hwa Park2, Suk Yeong Lee2, Jeong-Ho Lee1
출판정보	2013; 2013(1):
키워드	운동유발성급성신손상, 전산화단층촬영, 자기공명영상/Exercise-induced acute renal failure, CT, MRI
초록	Acute renal failure with severe loin pain induced by anaerobic exercise (ALPE) is a rare condition, develops in young healthy males after repeated anaerobic exercise which an intense power output per second or per minute such as a short-distance sprint, soccer, a swimming race, baseball, weight lifting, and a bicycle race. It is accompanied by wedge-shaped contrast enhancement on computed tomography (CT) without evidence of rhabdomyolysis. Clinical characteristics of ALPE include reversible kidney dysfunction and temporary multiple wedge-shaped delayed enhancements visible on CT. The pathogenesis of ALPE is thus suspected to involve temporary patchy ischemia of the kidney resulting from reversible vasoconstriction of the renal vessels. Although contrastenhanced CT is the gold standard for diagnosing ALPE, use of contrast media is potentially problematic for patients with renal dysfunction. On the other hand, the abnormal findings on diffusion-weighted magnetic resonance imaging (MRI) are known to suggest cytotoxic edema and/or vasogenic edema. In two adolescent cases with ALPE, we tried t determine the relationship between findings from CT and magnetic resonance imaging (MRI). Case 1 involved a 29-year-old male with a diagnosis of ALPE, and case 2 a 32-year-old male. A clear wedge-shaped signal hyperintensity matching the CT images was obtained by diffusion-weighted MRI. Here, we report the cases of two young patients with ALPE in whom temporary patchy ischemia could be identified by noninvasive diffusion-weighted MRI. In conclusions, diffusionweighted MRI is a very useful examination for diagnosing ALPE, providing noninvasive detection of lesions peculiar to ALPE.
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