대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	Kidney Transplantation Alone in ESRD Patients with Hepatitis B Liver Cirrhosis: A Single Center Experience
저자	Kyeongwoo Nho1, Young Hoon Kim2, Duck Jong Han2, Su-Kil Park1, Soon Bae Kim1
출판정보	2014; 2014(1):
키워드	신장이식, 간경화, B형 간염
초록	Background: KT alone in ESRD patients with HBV LC is controversial. This study compared outcomes of KT in HBsAg- positive patients with ESRD with (LC group) and without LC (Non-LC group). Methods: Outcomes were analyzed in103 HBsAg-positive patients with ESRD who underwent KT alone between 1997 and 2011. 91 were in the Non-LC group and 12 were in the LC group. Of the latter, eight were Child-Pugh (CP) class A and four were CP class B. Results: Baseline AST and ALT levels were higher in the LC group. MELD scores were similar in patients with CP class A and B, only serum albumin level was lower in CP class B. After KT, one CP class A patient showed an increase in the CP score from 5 to 10 points, MELD score from 22.3 to 44.1 points. The CP and MELD scores of the other 11 patients in the LC group did not increase. All four pre-KT CP class B patients were reclassified as class A after KT, because of elevated serum albumin levels. Four patients in the LC group developed HCC at a median of 35 months (range: 20-57 months) after KT. The 5 year patient survival rate was similar in the LC and Non-LC groups (100% vs. 94%, p= 0.15). The incidence of pre-KT LC did not differ between survivors and non-survivors (11% vs. 18%, p=0.61). Occurrence of HCC was significantly higher in non-survivors than in survivors. Conclusion: KT alone may be safe in patients with compensated HBV LC.
원문(PDF)	PDF 원문보기

목록

위로가기