대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	Clinical Outcome of BK Virus associated Nephropathy in Renal Transplant Recipients; Single Center Experience
저자	In-Ae Jang1, Hae Min Lee1, Bum Soon Choi1, Cheol Whee Park1,Yeong Jin Choi2, Chul Woo Yang1, Yong-Soo Kim1, Byung Ha Chung1
출판정보	2014; 2014(1):
키워드	신장이식, BK 바이러스, 신염
초록	Background: BK virus-associated nephropathy (BKVAN) is an important cause of allograft dysfunction in kidney transplant recipients. It has an unfavorable clinical course, and no definite treatment guideline has been established. We report here our center’s experience with biopsy-proven BKVAN cases and their clinical course. Methods: Between January 2004 and April 2013, 25 patients were found with BKVAN, as diagnosed by biopsy at Seoul St. Mary’s Hospital. Of the 25 patients, 10 were deceased-donor transplant recipients and the other 15 were living-donor transplant recipients. Three of the patients underwent retransplantation. The primary immunosuppressant used was cyclosporine in 8 patients and tacrolimus in 17 patients. Result: BKVAN was observed at a mean duration of 22.81±29.11 months after transplantation. The mean serum creatinine level at biopsy was 2.16±0.67 mg/dL. BKVAN occurred with acute rejection in 7 patients (28%). Immunosuppression modification was performed in 21 patients (84%). In addition, leflunomide and intravenous immunoglobulin were administered to 13 (52%) and 2 patients (8%), respectively. Total 5 cases (27.8%) of allograft loss developed for the follow-up periods of 0.7, 17.1, 21.8, 39.8 and 41.5 months from the BKVAN diagnosis. Advanced stage of BKVAN, increased creatinine and accompanied acute rejection at BKVAN diagnosis increased the risk for allograft failure.
원문(PDF)	PDF 원문보기

목록

위로가기