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논문분류	춘계학술대회 초록집
제목	Temporal Changes in Depression and Quality of Life in Incident Peritoneal Dialysis Patients
저자	Hye Eun Yoon, Yong-Soo Kim
출판정보	2014; 2014(1):
키워드	복막투석, 우울증, 삶의 질
초록	Aim: Temporal changes in depression and health-related quality of life (HRQOL) over time are not well described in peritoneal dialysis (PD) patients. Methods: A multicenter prospective observational study was conducted in 343 incident PD patients. Beck’s Depression Inventory (BDI) and Kidney Disease Quality of Life short form, version 1.3 were used to evaluate depression and HRQOL, respectively, at baseline and after 12 months. Results: The BDI score significantly increased after 12 months (p=0.039). Scores of physical role significantly increased, but scores of kidney disease-related symptom/problem list, sleep and social support significantly decreased after 12 months. Increase in serum albumin significantly predicted decrease in BDI score (β=-3.7, p=0.011). Charlson comorbidity index (β=-3.51, p=0.028) and increase in plasma hemoglobin (β=5.01, p=0.001) and serum albumin (β=11.29, p=0.048) were independently associated with increase in physical QOL scores. Decrease in adipose tissue index (β= -0.83, p=0.006) and increase in serum albumin (β = 6.88, p=0.001) significantly predicted increase in mental QOL scores. Charlson comorbidity index (β=-1.35, p=0.035) and decrease in peritoneal KT/Vurea (β=-2.7, p=0.007) significantly predicted increase in kidney-disease related QOL scores. Conclusion: In conclusion, depressive symptom is aggravated and HRQOL is impaired during 12 months in incident PD patients. Changes in nutrition, anemia, adipose tissue and dialysis adequacy are associated with changes in depressive symptoms and HRQOL.
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