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논문분류 춘계학술대회 초록집
제목 Comparison of Uremic Pruritus between Patients with Hemodialysis and Peritoneal Dialysis
저자 Ji Won Min1, Su-Hyun Kim2, Hyung Wook Kim1, Young Ok Kim1, Dong Chan Jin1,Ho Chul Song1, Euy Jin Choi1, Yong-Lim Kim3, Yon-Su Kim4, Shin-Wook Kang5,Nam-Ho Kim6, Chul Woo Yang1, Yong Kyun Kim1
출판정보 2014; 2014(1):
키워드 Uremic pruritus, Dialysis
초록 Background: Uremic pruritus is a common and unpleasant complication of End Stage Renal Disease (ESRD). In this study, we investigated and compared the prevalence of uremic pruritus, the intensity and distribution of itching sense of uremic pruritus between patients on HD and PD. Methods: A total of 425 HD and 223 PD patients from Clinical Research Center registry for ESRD cohort in Korea were assessed for the intensity of pruritus, scratching activity, distribution of pruritus and frequency of pruritus-related sleep disturbance by visual analogue scale (VAS) and questionnaire. Patients were categorized into two groups by the existence of pruritus. Patients were followed-up prospectively and median follow-up period was 18 months. Results: The prevalence of uremic pruritus was higher in PD patients than HD patients (62.6 %vs 48.3%, p=0.001). In patients with uremic pruritus, there was no significant difference in intensity of pruritus, scratching activity, distribution of pruritus and frequency of pruritus-related sleep disturbance between PD patients and HD patients. Kaplan- Meier analysis showed that the presence of uremic pruritus was not associated with mortality in HD patients (p= 0.174, Log-rank) as well as PD patients (p=0.685, Log-rank) Conclusions: Our data showed that uremic pruritus was more prevalent in PD patients than HD patients, while there was no difference in intensity and distribution of uremic pruritus between HD and PD patients.
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