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논문분류	춘계학술대회 초록집
제목	Impact of Dialysate Calcium Concentration on Mortality in Incident Hemodialysis Patients
저자	Kyung Yoon Chang1, Hyung Wook Kim1, Su-Hyun Kim2, Young Ok Kim1, Dong Chan Jin1,Ho Chul Song1, Euy Jin Choi1, Yong-Lim Kim3, Yon-Su Kim4, Shin-Wook Kang5,Nam-Ho Kim6, Chul Woo Yang1, Yong Kyun Kim1
출판정보	2014; 2014(1):
키워드	투석액 칼슘 농도, 혈액 투석, 사망률
초록	Background: The association between dialysate calcium (DCa) concentration and mortality in hemodilaysis (HD) patients is controversial. We evaluated the impact of DCa concentration on mortality in incident HD patient. Methods: Incident HD patients were selected from the Clinical Research Center (CRC) registry for end-stage renal disease (ESRD), a prospective cohort study on dialysis patients in Korea. Incident HD patients were categorized into three groups according to the DCa concentration prescribed at the time of enrollment. ‘High DCa’ was defined as DCa concentration=3.5 mEq/L, ‘mid DCa’ as DCa concentration=3.0 mEq/L, and ‘low DCa’ as DCa concentration= 2.5-2.6 mEq/L. The primary outcome was all-cause mortality. Results: A total of883 incident HD patients were included. The number of patients in ‘high DCa’ group was 155 (17.6%), ‘mid DCa’ group was 579 (65.6%)and ‘low DCa’ group was 149 (16.9%).The median follow-up period was 24 months. The ‘high DCa’ group had a significantly higher risk of all-cause mortality compared with the ‘mid DCa’ group (HR 2.24, 95 %CI, 1.18-4.24, p=0.013) and with ‘low DCa’ group (HR 8.17, 95 %CI, 1.84-36.30, p=0.006). There was no significant difference in mortality between the ‘mid DCa’ and the ‘low DCa’ group (HR 0.27, 95 %CI, 0.07-1.16, p=0.079) after adjustment for clinical variables. Conclusions: Our data showed that HD using high DCa was a significant risk factor for death in incident HD patients.
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