대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	The Association between Serum Alkaline Phosphatase and Mortality in Peritoneal Dialysis: A Multicenter Prospective Cohort Study
저자	Seon Deok Hwang1, Su-Hyun Kim2, Young Ok Kim1, Dong Chan Jin1, Ho Chul Song1,Euy Jin Choi1, Yong-Lim Kim3, Yon-Su Kim4, Shin-Wook Kang5, Nam-Ho Kim6,Chul Woo Yang1, Yong Kyun Kim1
출판정보	2014; 2014(1):
키워드	ALP, 복막투석, 생존률
초록	Background: Serum alkaline phosphatase (ALP) level has been reported to be associated with the mortality in hemodialysis patients. However, it is not well established whether serum ALP level is associated with mortality in peritoneal dialysis (PD) patients. The aim of this study was to determine the association between serum alkaline phosphatase levels and mortality in PD populations using the Clinical Research Center (CRC) registry for End Stage Renal Disease (ESRD) cohort in Korea. Methods: PD Patients were included from the CRC registry for ESRD, a multicenter prospective observational cohort study in Korea. Patients were categorized into three groups by tertile of serum ALP levels as follows: Tertile 1, ALP <78 U/L; Tertile 2, ALP=78-155 U/L; Tertile 3, ALP >155 U/L. Cox regression analysis was used to calculate the adjusted hazard ratio (HR) of mortality with a serum ALP levels of tertile 1 as the reference. Result: A total of 1,469 PD patients were included. The median follow-up period was 28 months. The multivariate Cox proportional hazard model showed that the higher tertiles of serum ALP levels were associated with higher mortality (Tertile 2: HR 1.98, 95% confidence interval (CI), 1.17-3.34, Tertile 3: HR 1.74, 95% CI, 1.01 to 3.02) after adjustment for clinical variables. Conclusions: Our data showed that increased serum alkaline phosphatase levels were significant risk factor for mortality in PD patients.
원문(PDF)	PDF 원문보기

목록

위로가기