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논문분류 춘계학술대회 초록집
제목 Relationship between Onodera’s Prognostic Nutritional Index and Subpopulation Lymphocyte Counts in Hemodialysis and Peritoneal Dialysis Patients
저자 Ye Na Kim1, Young Ju Ryu1, Gyoung-Hoon Kang1, Ho Sik Shin1,Yeon Soon Jung1, Hark Rim1, Hyun Yul Rhew2
출판정보 2014; 2014(1):
키워드 Onodera 예후영양지표, 림프구아수, 투석
초록 Background: No standard method for assessing the nutritional status in dialysis patients. In the present study, we undertook an evaluation to determine whether estimation of Onodera’s Prognostic Nutritional Index (OPNI) and lymphocyte subset counts can be helpful in diagnosis of malnutrition in hemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD) patients. Methods: We examined the OPNI and lymphocyte subset counts of 50 HD patients (55.8±12.7 years; 28 men and 22 women) and 16 CAPD patients (49.8±14.5 years; 10 men and 6 women). The OPNI is calculated based on the serum albumin level and total lymphocyte count and uses the following equation: OPNI=10×serum albumin (g/dL)+ 0.005×total lymphocyte count (/mL). Logistic regression analysis was performed for predicting malnutrition in dialysis patients. Results: The average OPNI value was 47.0±4.6 in HD patients and 39.5±4.3 in CAPD patients. Lymphocyte subset counts were not different between HD patients and CAPD patients. Lymphocyte subset counts were lower in patients with higher OPNI (OPNI ≥45). According to logistic regression for predicting malnutrition according to GNRI, age, CAPD and CD 19 count predicted malnutrition in hemodialysis and peritoneal dialysis patients Conclusions: These results suggest that OPNI and lymphocyte subset counts (especially CD 19 count) may be a significant nutritional marker in HD and CAPD patients.
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