대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	The Clinical Outcomes of Geriatric Kidney Transplantation in Korea
저자	Kyung Don Yoo1, Jung Nam An2, Young Hoon Kim3, Su Kil Park4, Dong-Wan Chae5,Yoon Kyu Oh2, Yon Su Kim1, Chun Soo Lim2, Jung Pyo Lee2
출판정보	2014; 2014(1):
키워드	신이식, 고령
초록	Background: Elderly individuals who underwent kidney transplantation are growing rapidly. Proportion of kidney transplant recipients older than 65 years increased from 9.5% to 18.4% between 2001 and 2011 according to the U.S. OPTN/SRTR annual report. According the KONOS data, about one-fifth patients of all listed candidates (22.4%) are older than 60 years old waiting for kidney transplantation. However, clinical outcomes in elderly patients were not well evaluated in Korea. Method: This is a multicenter cohort study included patient underwent kidney transplantation between 1997 and 2011 in 5 major tertiary hospitals in Korea. Patients under 18 years old were excluded. A total of 2614 kidney transplant patients were enrolled. Patient survival, allograft survival, and biopsy-proven acute rejection (BPAR) were monitored as end-points in elderly transplant patients comparing with younger population. Results: Participants older than 60 years old was 8.5% (N=223). Their mean age was 63.2±2.7 years old. Total patients were divided into 5 groups according to transplant age by 10 years. The male patients (69.5%), the prevalence of diabetes mellitus (39.0%), and history of ischemic heart disease (16.9%) were more in oldest age group (>60YO). Deceased donor transplantation was more frequent (34.1%). The over-all mortality rate was significantly higher in the oldest group (1 yr survival 96.0%, 5 yr survival 93.0%). However, age did not affect allograft survival (1 yr survival 96.8%, 5 yr survival 94.5% in the oldest group) and the prevalence of BPAR conversely decreased as the age increase. In recipients 60 years and older, BPAR was an independent risk factors for allograft loss after adjusting for age, gender, diabetes, hypertension, and donor type (p=0.029, hazard ration 2.86, 95% confidence interval 1.12-7.33). Conclusion: Kidney transplantation in the elderly is comparable to younger age. Episode of acute rejection could affect allograft survival.
원문(PDF)	PDF 원문보기

목록

위로가기