| 초록 |
A 32-year-old woman was admitted to our hospital, because of oliguria and progressive muscle weakness in her lower extremity. she began experiencing chill, malaise, myalgia, sore throat and cough from 7 day ago. Past medical history was herb medication for weight diet from 2 weeks ago and drugs medication for upper respiratory infection from 1 week ago. Laboratory findings suggested rhabdomyolysis complicated acute kidney injury. We suspected the Guillain Barre syndrome and drug induced rhabdomyolysis. So, continuos renal replacement therapy performed for the oliguric acute kidney injury. In addition nerve conduction study was performed but test result was normal. After, the patient complained of proximal muscle weakness in upper and lower extremity. So, the muscle biopsy was obtained from the left thigh and showed extensive myofiber necrosis with many inflammatory cell infiltration in perivascular area and around the individual muscle fiber. A diagnosis of polymyositis was based upon the progressive proximal muscle weakness on both upper and lower extremities, elevated muscle enzyme level, muscle biopsy findings. We report a case of polymyositis with rhabdomyolysis misdiagnosed as a Guillain Barre syndrome with literature. |