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논문분류	춘계학술대회 초록집
제목	Clinical Characteristics of Acute Kidney Injury in Patients with Acute Pyelonephritis-RIFLE Criteria Validation
저자	In O Sun, Byung Sun Kim, Woong Ki Lee, Hye Mi Choi, Choong Sil Seong,Hyeuk Soo Lee, Hyun Ju Yoon, Jeong Gwan Kim, Kwang Young Lee
출판정보	2014; 2014(1):
키워드	급성 신질환, 급성신우신염
초록	Background: The aim of this study is to investigate the incidence and clinical characteristics of acute kidney injury (AKI) based on the RIFLE criteria in acute pyelonephritis. Methods: From 2007 to 2012, 706 patients were diagnosed with acute pyelonephritis. Of these, we included 690 patients who were followed up until renal recovery or for at least three months. We evaluated the incidence, clinical characteristics, and severity of AKI based on the RIFLE classification. Results: Of the 690 patients, 164 had acute pyelonephritis-associated AKI. The incidence of AKI was 23.1%; of which, 10.8%, 10.0% and 2.3% were classified as Risk, Injury and Failure, respectively. In comparison with patients in the non-AKI group, the patients in the AKI group were older (65±15 vs 53±18 year, p=0.01) and had low albumin level (3.4±0.6 vs 3.8±0.6 mg/dL, p=0.01). Length of hospital stay, intensive care unit admission rate and proportion of hypertension were higher in patients with AKI than in those without. In the AKI group, 151 patients had AKI prior to admission, and 9 patients experienced AKI during their hospitalization. Multivariate analysis revealed that age; male gender; hypertension; complicated type of APN; leukocytosis; hypoalbuminemia were independent predictors for AKI in patients with acute pyelonephritis. Conclusion: The incidence of AKI in patient with acute pyelonephritis is 23.1%. We identified several factors associated with AKI. Recognition of these predictive factors may help reduce the incidence of acute pyelonephritis-associated AKI.
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