| 초록 |
Renovascular hypertension is an important, potentially correctable cause of hypertension particularly in older patients
with atherosclerotic vascular disease. Acute kidney injury or unexplained deterioration of kidney function during RAS
blockade and episodes of flash pulmonary edema are observed prior to diagnosing renal artery stenosis. Most renal
artery stenosis patients have moderate to severe hypertension. The gold standard for diagnosing tool of renal artery
stenosis is renal arteriography. However, noninvasive tests (duplex Doppler ultrasonography, computed tomographic
angiography and Magnetic resonance angiography) are reasonable alternatives for screening test.
The 2005 ACC/AHA guidelines recommend percutaneous revascularization for patients with hemodynamically significant
atherosclerotic renal artery stenosis, unexplained recurrent congestive heart failure (CHF), or sudden pulmonary
edema. Nevertheless, recent clinical trials and meta-analysis conclude that renal-artery stenting did not improve
outcomes (death, progression renal failure and need for renal replacement therapy) compared with medical therapy in
patients with moderate to severe atherosclerotic renal-artery stenosis. Medical therapy such as antiplatelet agents,
statins and RAS blockade is the optimal choice for the majority of these patients. Further studies should investigate to
identify patient subgroups that may benefit from renal-artery stenting. |