| 저자 |
Jeong Ho Kim1, Ji-Il Kim2, In Sung Moon2, Young Soo Kim1, Young Ok Kim1, Sun Ae Yoon1, Bum Soon Choi1, Cheol Whee Park1, Chul Woo Yang1, Yong-Soo Kim1, Byung Ha Chung1 |
| 초록 |
Purpose: In this study, we investigated the development of delayed graft function in kidney transplantation (KT) from deceased donors (DD) according to the severity of acute kidney injury based on various acute kidney injury (AKI) criteria.
Methods: We analyzed 285 kidney transplant recipients who took kidney from 228 deceased donors. We calculated the AKI stage of deceased donor according to the Risk, Injury, Failure, Loss of Kidney Function, and End-stage Kidney Disease (RIFLE), AKI Network (AKIN) and Kidney Disease: Improving Global Outcomes (KDIGO) criteria and compared the predictability for the development of delayed graft function (DGF) and the change of allograft function.
Results: For all classification systems, DGF developed more frequently in the AKI group than non-AKI group (p<.05) and allograft function assessed by the Modification of Diet in Renal Disease (MDRD) equation showed a significantly deteriorating pattern at 2 weeks and 1, 3, 6 months after KT compared to that in the non-AKI group (p<.05, comparison at each time point). In ROC analysis, the 3 criteria showed similar predictability in the prediction of the development of DGF.
Conclusions: In DDKT, the RIFLE, AKIN and KDIGO criteria showed similar prediction for the development of DGF. Also, no difference was detected in the prediction of allograft function during long term follow up. |