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논문분류	춘계학술대회 초록집
제목	Risk Factors of Hypertension after Living Donor Kidney Transplantation
저자	Hoon Yu1, Hyosang Kim1, Chung Hee Baek1, Eunhye Shin1, Hyungjin Cho1, Duck Jong Han2, Su-Kil Park1
출판정보	2015; 2015(1):
키워드	신장이식,고혈압,위험요인
초록	Background: Hypertension is very common in kidney transplant recipients after transplantation. It is associated with cardiovascular complication and poor graft survival in transplanted patients. The aim of this study is to evaluate possible factors associated with hypertension following kidney transplantation. Methods and Materials: The recipients who underwent living donor kidney transplantation at Asan Medical Center between January 2009 and April 2012 were enrolled. Patients were divided into two groups according to use of anti-hypertensive medication or not at 12 months after transplantation. Two groups of patients were compared in donor factors, recipient factors, characteristics at 12 months after transplantation. Results: Total 524 patients were enrolled. 484 patients (92%) had hypertension before transplantation. 353 patients (67%) had hypertension 12 months after transplantation. On univariate analysis, female donor, hypertensive donor, donated right kidney, male recipient, recipient left ventricular hypertrophy (LVH), number of initial anti-hypertensive medication >2, pre-transplant hypertension, high serum creatinine at 12 months after transplantation, high hemoglobin at 12 months, high body mass index (BMI) at 12 months and use of cyclosporine at 12 months were associated with hypertension. On multivariate analysis, male recipient (OR: 2.38; 95% CI: 1.32-4.29); pre-transplant hypertension (OR:4.82; 95% CI: 1.82-12.73); recipient LVH (OR:1.79; 95% CI: 1.07-2.99); Donor hypertension (OR:4.67; 95% CI: 1.19-18.43); cyclosporine use at 12 months after transplantation (OR: 2.00; 95% CI: 1.18-3.41); BMI>25 kg/m2 at 12 months after transplantation (OR: 3.63; 95% CI: 1.96-6.73) were associated with hypertension. Conclusion: These data show that male recipient, hypertension before transplantation, recipient LVH, hypertensive donor, obesity, cyclosporine use were independent factors associated with hypertension. It would be useful to predict and prevention the hypertension after kidney transplantation.
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