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논문분류	춘계학술대회 초록집
제목	Intra-dialytic Hypertension is Associated with High Mortality in Hemodialysis Patients
저자	Jae-Seok Park2, Sun-Hyo Lee1, Kyu-Tae Yoon1, Hyo-Wook Gil1, Jong-Oh Yang1, Eun Young Lee1, Sae-Yong Hong1
출판정보	2015; 2015(1):
키워드	혈액 투석,고혈압,사망률
초록	Bakground: Intra-dialytic hypertension (IDH) is emerging as an important issue in hemodialysis patients. However, the risk factors and clinical outcomes for IDH are unclear. Methods: In total, 15 patients with IDH and 59 patients without IDH patients were retrospectively investigated, with regard to their clinical and laboratory parameters, and mortality, over a period of 78 months. Results: Lower serum potassium (4.7±0.5 vs. 5.2±0.7 mmol/L, p=0.003) and urea nitrogen (13.7±5.2 vs. 19.9±5.9 mmol/L, p=0.004) levels were observed in the IDH group. The odds ratio of IDH was 0.1 (95% confidence interval [CI], 0.012-0.821, p=0.032) for each increase of 1.0 mmol/L in the serum potassium value in both male and female patients, and 0.905 (95% CI, 0.838 to 0.977, p=0.010) for each increase of 1.0 mmol/L in the urea nitrogen value in male patients. The prevalence of IDH was higher in male and female patients with a potassium level of <5.4 mmol/L (28.3 vs. 3.7%, p=0.012), and in male patients with a urea nitrogen level of <18.7 mmol/L (27.9 vs. 6.7%, p=0.023). Survival analysis showed significantly higher overall mortality in the IDH group (60.0 vs. 30.5%, p=0.034). Conclusion: IDH is associated with high mortality in hemodialysis patients. The risk factors for IDH are a serum potassium level of <5.4 mmol/L in male and female patients, and a urea nitrogen level of <18.7 mmol/L in male patients.
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